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Home » Central Nervous System » Eslicarbazepine Acetate 
 
Eslicarbazepine Acetate
 
Eslicarbazepine   Acetate is a prodrug which gets activated  to Eslicarbazepine (S-Licarbazepine), an active metabolite of  Oxcarbazepine. It  is a 3rd generation Anticonvulsant as well as Antiepileptic. drug licensed as an adjunctive treatment for partial onset seizure.      Eslicarbazepine Acetate blocks the voltage gated Na+ ion channel, which inhibits repetitive firing ,   stabilize hyper excited neuronal membrane and decrease the release of synaptic  impulse making   brain cells remain less excitable
 
 
Molecular structure :
CAS Number: 236395-14-5
Molecular formula: C17H16N2O3
Application:
Eslicarbazepine Acetate  is used for treatment of  Epilepsy , Partial Onset Seizure , Bipolar disorder, rigeminal neuralgia.
Advantage:
  • Eslicarbazepine Acetate provide treatment with once daily administration, this also leads to reduction in side effects.
  • Effective reduction in frequency of seizure
  • Improved efficacy than the older medication
  • Not affected by the pH of the gut
Innovator: Eisai
Brand name: Zebinix
 
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